NYHA class III-IV
Atrial fibrillation
Severe valve heart disease
LVEF: %
Anemia Hemoglobin < 11 g/dl
Complicated diabetes Diabetes with retinopathy, neuropathy, nephropathy, coronary artery disease or peripheral vessel disease
Hypertension Blood pressure > 140/90 mmHg
Creatinine: mg/dl
No Beta-blockers
No ACE-inhibitors/ARBs
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